HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21255118, compound → HCID 21255199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21255118 | HCID 21255118 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 21255199 | HCID 21255199 | 84.1% |
Reaction Steps
2-Chloro-3-(3-pyridyl)-5,6,7,8-tetrahydroindolizine-1-carboxylic acid is prepared as in Example 44, from 0.9 g of methyl 2-chloro-3-(3-pyridyl)-5,6,7,8-tetrahydroindolizine-1-carboxylate. 0.72 g of 2-chloro-3-(3-pyridyl)-5,6,7,8-tetrahydroindolizine-1-carboxylic acid are thus obtained in the form of a white powder (Rf=0.43; thin layer chromatography on silica gel; eluent: 9/1 dichloromethane/methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194426B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-1ee9ddcdedb646b28741c5a468906876 |
| Source note | uspto-grants-2001_02 |