Ethanol → HCID 22611021, compound

HRID 636680Notes

Reaction equation

HRID 636680 reaction equation
[N+:1]([C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1)([O-])=O.O.O.O.O.O.O.O.O.O.[S-2].[Na+].[Na+].[Cl-].[NH4+].C(O)C>O>[NH2:1][C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 25517Ammonium ChlorideHCID 73972Sodium sulfide nonahydrateHCID 18522031HCID 18522031, compound

Product 1

HCID 22611021HCID 22611021, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2-nitro-N-(4-(2-thiazolylamino)phenyl)aniline (1.2 g, 3.8 mmol), sodium sulfide nona hydrate (4.61, 19.2 mmol), ammonium chloride (1.03 g, 19.2 mmol) and ethanol (40 ml) was stirred at reflux for 40 h. Water (50 ml) was added, the mixture was stirred an d filtered. Yield 0.49 g, 46%. M.p. 184-186° C.

Workup

  1. temperatureat reflux for 40 h
  2. stirringthe mixture was stirred an d
  3. filtrationfiltered

Sources & evidence

ORD record
ord-02188d11568d4ab08211d4463fe34ac1
Source dataset
uspto-grants-2001_02
Patent number
US06194447B1

Reaction notes

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