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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 636697Generated: October 29, 2026

1-(2-Iodoethyl)-4-nitrobenzene → 2-Amino-3-(4-chloro-benzoyl)-6-[4-nitro-(2-phenyleth-1-yl)]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

https://huagongshe.com/reaction/636697

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Iodoethyl)-4-nitrobenzeneHCID 11346446—
Reactant2-Amino-3-(4-chlorobenzoyl)-4,5,6,7-tetrahydrothieno(2,3-c)pyridineHCID 15434455—
Product2-Amino-3-(4-chloro-benzoyl)-6-[4-nitro-(2-phenyleth-1-yl)]-4,5,6,7-tetrahydrothieno[2,3-c]pyridineHCID 15434452—

Reaction Steps

The same procedure as in Example 17 was used except an equivalent amount of 2-amino-3-(4-chloro-benzoyl) 4,5,6,7-tetrahydrothieno[2,3-c]pyridine is used in place of 2-Amino-3-benzoyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine (2 mmol), and an equivalent amount of p-nitrophenylethyl iodide was used in place of methyl iodide (3 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06194449B1
Source datasetuspto-grants-2001_02
ORD IDord-d7550a91c1f7461a8c9e581bc458cf91
Source noteuspto-grants-2001_02