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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63680Generated: October 26, 2026

1-Bromo-3-methylbutan-2-one → 4-Isopropyl-thiazole-2-carboxamidine

https://huagongshe.com/reaction/63680

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-methylbutan-2-oneHCID 10899037—
Reactant4-Cyclopropyl-thiazole-2-carboxamidineHCID 90000916—
Product4-Isopropyl-thiazole-2-carboxamidineHCID 89996151—

Reaction Steps

4-Isopropyl-thiazole-2-carboxamidine (Compound V) was prepared in analogy to Compound M with procedure shown in Example 10 by using 1-bromo-3-methyl-butan-2-one instead of 2-bromo-1-cyclopropyl-ethanone. MS: calc'd (MH+) 170, measured (MH+) 170.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447086B2
Source datasetuspto-grants-2016_09
ORD IDord-425468a008e94181855ed6b1cddfc0ba
Source noteuspto-grants-2016_09