HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18464792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Thioanisole | HCID 7520 | — |
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | HCID 18464551 | HCID 18464551 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 18464792 | HCID 18464792 | — |
Reaction Steps
Combine 2-(4-bromobenzyloxy)ethyl trifluoromethyl ether (2.4 g, 8.1 mmol), thioanisole (28.5 mL, 243 mmol), and trifluoroacetic acid (30 mL). After 24 hours, add potassium bicarbonate to neutralize. Add MgSO4 and chloroform (30 mL). Filter and distill through a short path distillation apparatus to give 2-(trifluoroacetoxy)ethyl trifluoromethyl ether containing chloroform which can be used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194406B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-fa7260bd6b30444fbdbb8f914d2cf58f |
| Source note | uspto-grants-2001_02 |