Water → HCID 20218251, compound

HRID 637267Notes

Reaction equation

HRID 637267 reaction equation
[N+:1]([C:4]1[CH:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][C:20]=2[Cl:29])=[CH:14][C:5]=1[O:6][CH2:7][P:8](=[O:13])([O:11]C)[O:9]C)([O-:3])=[O:2].O>Cl>[N+:1]([C:4]1[CH:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:26])[F:27])=[CH:21][C:20]=2[Cl:29])=[CH:14][C:5]=1[O:6][CH2:7][P:8](=[O:9])([OH:13])[OH:11])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 962WaterHCID 13343565HCID 13343565, compound

Product 1

HCID 20218251HCID 20218251, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Dimethyl 2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxymethylphosphonate (1 g) in 20 ml of 6N hydrochloric acid is heated under reflux overnight. The solution is then poured into water and the mixture is extracted with methylene chloride. The combined solvent extracts are dried over magnesium sulfate and the solvent is then evaporated off to give 2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxymethylphosphonic acid.

Workup

  1. temperatureunder reflux overnight
  2. extractionthe mixture is extracted with methylene chloride
  3. dry with materialThe combined solvent extracts are dried over magnesium sulfate
  4. customthe solvent is then evaporated off

Sources & evidence

ORD record
ord-099af53566f9462b8de1dcaf0dcd01c3
Source dataset
uspto-grants-1985_12
Patent number
US04556520

Reaction notes

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