Hydrochloric Acid → HCID 70381945, compound

Participants

Reaction Steps

A slurry of 0.5 g. (2.6 mmole) of 5-amino-2-oxindole-1-carboxamide and 0.35 g. of 4-(N,N-dimethylamino)pyridine was stirred at 10° C., and then 0.20 ml. (2.8 mmole) of acetyl chloride was added. Stirring was continued at ca -10° C. for 20 minutes and at room temperature for 15 minutes, and then 20 ml. of 1N hydrochloric acid was added. The solid was recovered by filtration, and dried, to give 0.20 g. of the title compound as a cream-colored solid.

Provenance & Evidence