HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 1-[2-(2,4-Dichlorophenyl)-pentylidene]-2-ethoxycarbonylhydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrazinecarboxylic acid, ethyl ester | HCID 20064 | — |
| Reactant | 2-(2,4-Dichlorophenyl)pentanenitrile | HCID 3324522 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-[2-(2,4-Dichlorophenyl)-pentylidene]-2-ethoxycarbonylhydrazine | HCID 53963328 | — |
Reaction Steps
22.8 g (0.1 mol) of 2-(2,4-dichlorophenyl)-valeronitrile, 10.4 g (0.1 mol) of hydrazinecarboxylic acid ethyl ester and 6.0 g (0.1 mol) of acetic acid are hydrogenated with 11.0 g of Raney nickel in 100 ml of 95% aqueous methanol at room temperature under a normal pressure of hydrogen for 4.5 hours. Filtration and crystallisation yield 22.1 g (70% of theory) of the above product; m.p. 127°-129° C.:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04556717 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-c582238550314889b33708bd125f639b |
| Source note | uspto-grants-1985_12 |