反应详情

22.8 g (0.1 mol) of 2-(2,4-dichlorophenyl)-valeronitrile, 10.4 g (0.1 mol) of hydrazinecarboxylic acid ethyl ester and 6.0 g (0.1 mol) of acetic acid are hydrogenated with 11.0 g of Raney nickel in 100 ml of 95% aqueous methanol at room temperature under a normal pressure of hydrogen for 4.5 hours. Filtration and crystallisation yield 22.1 g (70% of theory) of the above product; m.p. 127°-129° C.:

1. filtrationFiltration and crystallisation yield 22.1 g (70% of theory) of the above product