Acetic Acid → 1-[2-(2,4-Dichlorophenyl)-pentylidene]-2-ethoxycarbonylhydrazine

HRID 637514Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 637514
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH2:12][CH2:13][CH3:14])[C:10]#[N:11].[CH2:15]([O:17][C:18]([NH:20]N)=[O:19])[CH3:16].C(O)(=O)C.[H][H]>[Ni].CO>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH2:12][CH2:13][CH3:14])[CH:10]=[N:11][NH:20][C:18]([O:17][CH2:15][CH3:16])=[O:19]

Komponenten

7

Edukt 4

HCID 176Acetic AcidHCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 33245222-(2,4-Dichlorophenyl)pentanenitrileHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 539633281-[2-(2,4-Dichlorophenyl)-pentylidene]-2-ethoxycarbonylhydrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

22.8 g (0.1 mol) of 2-(2,4-dichlorophenyl)-valeronitrile, 10.4 g (0.1 mol) of hydrazinecarboxylic acid ethyl ester and 6.0 g (0.1 mol) of acetic acid are hydrogenated with 11.0 g of Raney nickel in 100 ml of 95% aqueous methanol at room temperature under a normal pressure of hydrogen for 4.5 hours. Filtration and crystallisation yield 22.1 g (70% of theory) of the above product; m.p. 127°-129° C.:

Aufarbeitung

  1. filtrationFiltration and crystallisation yield 22.1 g (70% of theory) of the above product

Quellen und Nachweise

ORD-Eintrag
ord-c582238550314889b33708bd125f639b
Quelldatensatz
uspto-grants-1985_12
Patentnummer
US04556717

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