Hydrogen Bromide → HCID 178447481, compound

HRID 637566Notes

Reaction equation

C[O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13]C)[NH:9][C:8](=[O:15])[N:7]=[C:6]2[CH3:16].C([O:19][C:20](=[O:25])[CH2:21][CH2:22][CH2:23][CH3:24])C.Br>>[OH:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[OH:13])[NH:9][C:8](=[O:15])[N:7]=[C:6]2[CH3:16].[C:20]([OH:25])(=[O:19])[CH2:21][CH2:22][CH2:23][CH3:24]

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 178447540HCID 178447540, compound

Product 1

HCID 178447481HCID 178447481, compound

Procedure

When 6,7-dimethoxy-4-methyl-2(1H)quinazolinone-1-pentanoic acid ethyl ester is hydrolyzed with 40% aqueous HBr for 24 hours as in Example 27 the title compound is obtained.

Sources & evidence

ORD record: ord-a42fb194a53647f3a47f1748710c10bc
Source dataset: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04556739

Reaction notes

Loading…