N-Methylbenzylamine → HCID 13343524, compound

HRID 637703Notes

Reaction equation

[CH2:1]([NH:8][CH3:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:10][N:11]1[C:15]2[CH:16]=[CH:17][C:18]([CH2:20][CH2:21]Br)=[CH:19][C:14]=2[O:13][C:12]1=[O:23]>>[CH3:10][N:11]1[C:15]2[CH:16]=[CH:17][C:18]([CH2:20][CH2:21][N:8]([CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH3:9])=[CH:19][C:14]=2[O:13][C:12]1=[O:23]

Participants

Reactant 2

HCID 7669N-Methylbenzylamine

HCID 13306088HCID 13306088, compound

Product 1

HCID 13343524HCID 13343524, compoundYield 65%

Procedure

By following the procedure indicated in Example 6, but starting from 0.04 mol (4.90 g) of N-benzyl-N-methylamine and 0.02 mol (5.10 g) of 3-methyl-6-(2-bromoethyl)-benzoxazolinone, 3.85 g of the title compound having a melting point of 72°-73° C. were obtained after recrystallisation from hexane.

Sources & evidence

ORD record: ord-cf23ecc53d8247758c5489ce4bc4a605
Source dataset: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04558060

Reaction notes

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