Isopropylamine → HCID 131714113, compound

HRID 637834Notes

Reaction equation

HRID 637834 reaction equation
[Cl:1]C1C=C(C=C(Cl)C=1)OCCCCl.[Cl:14][C:15]1[CH:16]=[C:17]([CH:23]=[C:24]([Cl:26])[CH:25]=1)[O:18][CH2:19][CH2:20][CH2:21]Br.[CH:27]([NH2:30])([CH3:29])[CH3:28]>C(Cl)(Cl)Cl>[ClH:1].[Cl:14][C:15]1[CH:16]=[C:17]([CH:23]=[C:24]([Cl:26])[CH:25]=1)[O:18][CH2:19][CH2:20][CH2:21][NH:30][CH:27]([CH3:29])[CH3:28]

Participants

5

Reactant 3

HCID 6363IsopropylamineHCID 20256299HCID 20256299, compoundHCID 22246762HCID 22246762, compound

Product 1

HCID 131714113HCID 131714113, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Following the procedure of Preparation 1, a mixture of 3-[3,5-dichlorophenoxy]-1-chloropropane and 3-[3,5-dichlorophenoxy]-1-bromopropane and isopropyl amine were reacted in refluxing chloroform overnight and the reaction mixture processed to yield an oil, the free base of the title compound. A portion of the oil was reacted with ethereal hydrogen chloride to form the hydrochloride salt; m.p. 157°-159° C.

Workup

  1. customthe procedure of Preparation 1
  2. customwere reacted
  3. customto yield an oil

Sources & evidence

ORD record
ord-ae3fac0fb0b543e3a06771fb01bfb2f1
Source dataset
uspto-grants-1985_12
Patent number
US04558155

Reaction notes

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