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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63793Generated: October 30, 2026

Ethyl isocyanate → 1-Ethyl-3-[4-(6-(dimethylaminomethyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]urea

https://huagongshe.com/reaction/63793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isocyanateHCID 8022—
ReactantHCID 117987912HCID 117987912—
SolventDichloromethaneHCID 6344—
Product1-Ethyl-3-[4-(6-(dimethylaminomethyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]ureaHCID 72548383—

Reaction Steps

Compound 13a (0.15 mmol) was dissolved in 10 mL of anhydrous dichloromethane, and 3 equiv of ethyl isocyanate was added and stirred at room temperature overnight. The target compound was obtained by filtration.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447101B2
Source datasetuspto-grants-2016_09
ORD IDord-88fec49bf0194ab695331aee6878ea20
Source noteuspto-grants-2016_09