Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 54036785 | HCID 54036785 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86740556 | HCID 86740556 | — |
Reaction Steps
A solution of ethyl 4,6-dichloro-2-pyrimidinylthioacetate (6 g) in acetonitrile (25 ml) is treated with a 33% aqueous solution of dimethylamine (6.4 ml). The mixture is left to stand at room temperature for 1 hour, then is cooled for 2 hours at 0° C. The precipitate is filtered, washed with a small quantity of acetonitrile: 4.85 g of the desired product are obtained (III, 29).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04559345 |
|---|
| Source dataset | uspto-grants-1985_12 |
|---|
| ORD ID | ord-b3632ff075414039b7da6d4b1ba4c10b |
|---|
| Source note | uspto-grants-1985_12 |
|---|
