反应详情

Cyclohexylamine (1.14 ml, 0.01 mole) and 7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (0.5 g, 0.003 mole) were heated at reflux in dry xylene (3 ml) for 48 h. The solvent was removed under reduced pressure and the residue crystallised from ethyl acetate/ether/pentane to give the title compound as a white solid (112 mg, 16%), m.p. 287°-289° C.

1. customThe solvent was removed under reduced pressure
2. customthe residue crystallised from ethyl acetate/ether/pentane