HCID 20255191, compound → HCID 20255126, compound

Participants

Reaction Steps

24.3 g of crude 1-[N-benzyl-[2-(3-carbamoyl-4-hydroxyphenoxy)-ethylamino]]-3-[4-(1-methyl-3-methylsulphonyl-1H-1,2,4-triazol-5-yl)-phenoxy]-2-propanol are catalytically debenzylated analogously to Example (4) and for working up, the crystalline precipitate is dissolved in dioxan by heating. Recrystallisation from methanol/dioxan yields 1-[2-(3-carbamoyl-4-hydroxyphenoxy)-ethylamino]-3-[4-(1-methyl-3-methylsulphonyl-1H-1,2,4-triazol-5-yl)-phenoxy]-2-propanol having a melting point of 190°-191°.

Provenance & Evidence