Propionyl chloride → HCID 13604086, compound

Participants

Reaction Steps

To 1,2-dichloroethane (50 ml) were added ethyl 7-chloro-2,3-dihydro-6-methoxybenzofuran-2-carboxylate (1b) (4.25 g, 0.01656 mol) and propionyl chloride (2.58 ml, 0.03311 mol). The solution was stirred on an ice bath and treated with anhydrous aluminum chloride (6.62 g, 0.04967 mol) at 0°-5° C. for 45 minutes. An additional portion of aluminum chloride (2.21 g, 0.01656 mol) was added and the mixture left to stir overnight.

Provenance & Evidence