反应详情

A solution of 0.35 g of sodium and 2 ml (about 0.017 mol) of benzylmercaptan in 100 ml of dioxane was added to a solution of 6.3 g (0.015 mol) of 6-chloro-4,7-dimorpholino-2-piperazino-pteridine in 200 ml of dioxane, and the resulting mixture was refluxed for about 2 hours. The solvent was substantially distilled off in vacuo and the residue was taken up in about 200 ml of water. After it had solidified, the reaction product was suction-filtered off, washed with water and dried in vacuo at room temperature.

1. temperaturethe resulting mixture was refluxed for about 2 hours
2. distillationThe solvent was substantially distilled off in vacuo
3. filtrationthe reaction product was suction-filtered off
4. washwashed with water
5. customdried in vacuo at room temperature