Piperazine → 4,7-Pteridinediamine, 6-chloro-N(sup 4),N(sup 4)-dimethyl-N(sup 7)-(phenylmethyl)-2-(1-piperazinyl)-

HRID 638182Notes

Reaction equation

HRID 638182 reaction equation
Cl[C:2]1[N:11]=[C:10]([N:12]([CH3:14])[CH3:13])[C:9]2[C:4](=[N:5][C:6]([NH:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:7]([Cl:15])[N:8]=2)[N:3]=1.[NH:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[Cl:15][C:7]1[N:8]=[C:9]2[C:4](=[N:5][C:6]=1[NH:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[N:3]=[C:2]([N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1)[N:11]=[C:10]2[N:12]([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 11792051HCID 11792051, compound

Product 1

HCID 30246554,7-Pteridinediamine, 6-chloro-N(sup 4),N(sup 4)-dimethyl-N(sup 7)-(phenylmethyl)-2-(1-piperazinyl)-

Procedure

This compound was prepared analogous to Example 1 from 2,6-dichloro-4-dimethylamino-7-benzylamino-pteridine and piperazine.

Sources & evidence

ORD record
ord-92f4c5f1279b48eb97904080addd5d6e
Source dataset
uspto-grants-1985_12
Patent number
US04560685

Reaction notes

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