Piperazine → 6-Chloro-2-piperazino-4-thiomorpholino-7-dimethylamino-pteridine

HRID 638184Notes

Reaction equation

HRID 638184 reaction equation
Cl[C:2]1[N:11]=[C:10]([N:12]2[CH2:17][CH2:16][S:15][CH2:14][CH2:13]2)[C:9]2[C:4](=[N:5][C:6]([N:19]([CH3:21])[CH3:20])=[C:7]([Cl:18])[N:8]=2)[N:3]=1.[NH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>>[Cl:18][C:7]1[N:8]=[C:9]2[C:4](=[N:5][C:6]=1[N:19]([CH3:21])[CH3:20])[N:3]=[C:2]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[N:11]=[C:10]2[N:12]1[CH2:17][CH2:16][S:15][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20253578HCID 20253578, compound

Product 1

HCID 133716826-Chloro-2-piperazino-4-thiomorpholino-7-dimethylamino-pteridine

Procedure

This compound was prepared analogous to Example 1 from 2,6-dichloro-4-thiomorpholino-7-dimethylamino-pteridine and piperazine.

Sources & evidence

ORD record
ord-b53eff17e44142aeb26749437f9040cc
Source dataset
uspto-grants-1985_12
Patent number
US04560685

Reaction notes

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