HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13336325, compound → HCID 20253561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13336325 | HCID 13336325 | — |
| Reactant | Hydrate;hydrochloride | HCID 21885828 | — |
| Product | HCID 20253561 | HCID 20253561 | 190.3% |
Reaction Steps
A mixture of said product (6.35 g) obtained in Step (a) and conc.hydrochloric acid-water (1:1) mixture (50 ml) is refluxed over a period of 20 hours. The reaction mixture is concentrated in vacuo to give 4-[4-chloro-2-(2-fluorobenzoyl)anilino]piperidine hydrochloride (5.51 g) as crystals melting at 225° to 228° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04560684 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-7b42797a4d974e338d8264f62d07eee3 |
| Source note | uspto-grants-1985_12 |