Methyl propiolate → HCID 10377790, compound

HRID 638200Notes

Reaction equation

HRID 638200 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:15])[CH:11]=[C:12]([CH3:14])[NH2:13])=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:16](OC)(=[O:19])[C:17]#[CH:18]>CN(C)C=O>[CH3:14][C:12]1[NH:13][C:16](=[O:19])[CH:17]=[CH:18][C:11]=1[C:10](=[O:15])[C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 13536Methyl propiolateHCID 70354449HCID 70354449, compound

Product 1

HCID 10377790HCID 10377790, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

m.p. 282°-284° C., 5.0 g, was obtained following the procedure described in Example A-2 using 20 g of 3-(4-nitrophenyl)-1-methyl-3-oxo-1-propenamine, 9.5 ml of methyl propiolate and 100 ml of dimethylformamide.

Workup

  1. customm.p. 282°-284° C., 5.0 g, was obtained

Sources & evidence

ORD record
ord-ed383774f61241a79ad1ee29c50db8f3
Source dataset
uspto-grants-1985_12
Patent number
US04560691

Reaction notes

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