tert-Butoxy bis(dimethylamino)methane → HCID 53847223, compound

HRID 638205Notes

Reaction equation

HRID 638205 reaction equation
[Br:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([C:8]2[CH:9]=[CH:10][C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[O:7])=[CH:4][CH:3]=1.[CH3:18][N:19]([CH:21](N(C)C)OC(C)(C)C)[CH3:20]>O1CCOCC1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[CH:9]=[CH:10][C:11](=[O:15])[NH:12][C:13]=2[CH:14]=[CH:18][N:19]([CH3:21])[CH3:20])=[O:7])=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 21779937HCID 21779937, compound

Product 1

HCID 53847223HCID 53847223, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

m.p. 265°-268° C. with decomposition, 53.8 g, was prepared following the procedure described in Example B-2 using 44 g of 5-(4-bromobenzoyl)-6-methyl-2(1H)-pyridinone, 300 ml of p-dioxane and 35 ml of bis-(dimethylamino)-t-butoxymethane.

Workup

  1. customm.p. 265°-268° C. with decomposition, 53.8 g, was prepared

Sources & evidence

ORD record
ord-7f7794d30b2b4a3290a99ef9484fbc0a
Source dataset
uspto-grants-1985_12
Patent number
US04560691

Reaction notes

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