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HRID638236

反应详情

EQUATION

反应方程式

HRID 638236 的结构方程式

REACTANTS

反应物

2
结构：COc1c(C)cnc(CCl)c1C
HCID819992

2-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine

C9H12ClNO

结构：FC1(F)Oc2cc3nc(S)[nH]c3cc2O1
HCID178506005

未命名化合物

PRODUCTS

生成物

1
结构：COc1c(C)cnc(CSc2nc3cc4c(cc3[nH]2)OC(F)(F)O4)c1C
HCID20253699

未命名化合物

收率 86%

PROCEDURE

实验过程

Analogous reaction of 2,2-difluoro-5H-[1,3]-dioxolo[4,5-f]benzimidazole-6-thiol with 2-chloromethyl-4-methoxy-3,5-dimethylpyridine gives 2,2-difluoro-6-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylthio]-5H-[1,3]-dioxolo[4,5-f]benzimidazole, of m.p. 148°-149° C. (from acetonitrile), in 86% yield.