HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66744955, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-Chloro-2-fluoro-6-(trifluoromethyl)benzaldehyde | HCID 736337 | — |
| Reactant | 5-Chloro-2-(difluoromethoxy)benzaldehyd | HCID 4770949 | — |
| Product | HCID 66744955 | HCID 66744955 | — |
Reaction Steps
Intermediate 16 was made in a similar manner as Intermediate 15 substituting 3-chloro-2-fluoro-6-(trifluoromethyl)benzaldehyde for 5-chloro-2-(difluoromethoxy) benzaldehyde followed by TFA deprotection. MS (ESI) m/z: 292 (M+Na)+. 1H NMR (400 MHz, CDCl3) δ 7.87 (1H, dd, J=16.17, 2.02 Hz), 7.49-7.62 (2H, m), 6.67 (1H, dd, J=16.30, 1.39 Hz) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447110B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-748906ec93a946de997697d1b42a06f3 |
| Source note | uspto-grants-2016_09 |