反应详情

A mixture of 10 g (36.4 mmol) of 4-chloro-2-(4-chlorophenyl)quinoline, and 20 ml of ethyl isonipecotate was stirred and heated at 160°-170° for 2 hr. It was then cooled and diluted with 200 ml of water and 5 ml of ethanol. The solid which formed was collected, and recrystallized from ethanol to give 5.5 g of product ester, mp 124°-126°.

1. temperatureheated at 160°-170° for 2 hr
2. temperatureIt was then cooled
3. customThe solid which formed
4. customwas collected
5. customrecrystallized from ethanol