反应详情

A mixture of 20 g (0.147 mol) of N-methylisonicotinamide, 100 ml of ethanol, and 1.2 g of platinum oxide was hydrogenated in a Parr shaker at 60° and 60 psi for 8 hr. The catalyst was filtered off, and the filtrate was concentrated in vacuo. The residue was crystallized from ether to give 20.5 g of crude product, mp 115°-121°.

1. customwas hydrogenated in a Parr shaker at 60°
2. filtrationThe catalyst was filtered off
3. concentrationthe filtrate was concentrated in vacuo
4. customThe residue was crystallized from ether