Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 638268Generated: October 26, 2026

Ethanol → 1-[2-(4-Chlorophenyl)-4-quinolinyl]-4-piperidinecarboxamide

https://huagongshe.com/reaction/638268

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant4-PiperidinecarboxamideHCID 3772—
Reactant4-Chloro-2-(4-chlorophenyl)quinolineHCID 11219546—
SolventPhenolHCID 996—
Product1-[2-(4-Chlorophenyl)-4-quinolinyl]-4-piperidinecarboxamideHCID 13603914—

Reaction Steps

In a manner analogous to that of Example 6, 4-chloro-2-(4-chlorophenyl)quinoline was reacted with isonipecotamide in phenol at 170° C., yielding the named compound, mp. 245°-247° dec., from ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04560692
Source datasetuspto-grants-1985_12
ORD IDord-dfb63a18cc624a76ac643089f08d8317
Source noteuspto-grants-1985_12