Propylamine → HCID 13603918, compound

HRID 638278Notes

Reaction equation

HRID 638278 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[N:18]1[CH2:23][CH2:22][CH:21]([C:24](Cl)=[O:25])[CH2:20][CH2:19]1.[CH2:27]([NH2:30])[CH2:28][CH3:29]>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[N:18]1[CH2:23][CH2:22][CH:21]([C:24]([NH:30][CH2:27][CH2:28][CH3:29])=[O:25])[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 7852PropylamineHCID 13603937HCID 13603937, compound

Product 1

HCID 13603918HCID 13603918, compound

Procedure

In a manner analogous to that of Example 1(e) but using 1-[6-Fluoro-2-phenyl-4-quinolinyl]-4-piperidinecarbonyl chloride and propylamine as starting materials the named compound was obtained as off-white needles, mp 196°-198° dec. after recrystallization from methanol.

Workup

  1. customwas obtained as off-white needles, mp 196°-198° dec.
  2. customafter recrystallization from methanol

Sources & evidence

ORD record
ord-634ce4ee9c9c4b53b99e5b4bc226659d
Source dataset
uspto-grants-1985_12
Patent number
US04560692

Reaction notes

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