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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 638290Generated: October 31, 2026

Phosphorus oxychloride → 4,6-Dichloroquinoline

https://huagongshe.com/reaction/638290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178516411HCID 178516411—
Product4,6-DichloroquinolineHCID 936075—

Reaction Steps

From 93.6 g of 6-chloro-4-hydoxyquinoline and 200 ml of phosphorus oxychloride reacted in a manner similar to that described in Example 2(b) there was obtained 63.6 g of the above named compound as white needles, mp 101°-104°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04560692
Source datasetuspto-grants-1985_12
ORD IDord-b90b6f26cb704649b24b81b4c3efc9cf
Source noteuspto-grants-1985_12