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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 638296Generated: October 30, 2026

Phosphorus oxychloride → 4,6-Dichloro-2-phenylquinoline

https://huagongshe.com/reaction/638296

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178515553HCID 178515553—
Product4,6-Dichloro-2-phenylquinolineHCID 13603938—

Reaction Steps

From 25.5 g of 6-chloro-2-phenyl-4-quinolinol and 50 ml of phosphorus oxychloride treated according to the procedure of Example 4(b) there was obtained 24.86 g of 4,6-dichloro-2-phenylquinoline, mp 114°-116°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04560692
Source datasetuspto-grants-1985_12
ORD IDord-d8bf31bbd7074920a2317e38d911e4b1
Source noteuspto-grants-1985_12