Glutaraldehyde → HCID 20254306, compound

HRID 638341Notes

Reaction equation

HRID 638341 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[CH2:10]([CH2:14][CH:15]=[O:16])[CH2:11][CH:12]=O.[CH2:17]([C:24](O)=O)[C:18](CC(O)=O)=O.C([O-])(=O)C.[Na+]>Cl.O>[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][N:7]2[CH:10]3[CH2:11][CH2:12][CH2:24][CH:17]2[CH2:18][C:15](=[O:16])[CH2:14]3)=[CH:4][CH:3]=1

Participants

7

Reactant 4

HCID 3485GlutaraldehydeHCID 660354-MethylbenzylamineHCID 68328Acetonedicarboxylic acidHCID 517045Sodium Acetate

Product 1

HCID 20254306HCID 20254306, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolvent2×HCID 962WaterSolvent2×

Procedure

A solution of 4-methylbenzylamine (12 g) in dilute hydrochloric acid (5N, 20 ml) was added to glutaric dialdehyde (50%, 24 ml) in water (100 ml) with stirring. A solution of 1,3-acetonedicarboxylic acid (14.6 g) and sodium acetate (8.2 g) in water (100 ml) was then added and the mixture stirred for 24 hours at room temperature. A further quantity of dilute hydrochloric acid (5 ml) was then added and the mixture stirred for a further 48 hours.

Workup

  1. stirringthe mixture stirred for 24 hours at room temperature
  2. stirringthe mixture stirred for a further 48 hours

Sources & evidence

ORD record
ord-d0171238922f411097472cb606de2d7d
Source dataset
uspto-grants-1985_12
Patent number
US04560757

Reaction notes

Loading…