反应详情

To a solution of sodium (4.6 g, 0.2 mole) in anhydrous methanol (140 ml) at 25° C. was added 4-nitro-2-picoline-N-oxide (31 g, 0.2 mole). The mixture was stirred for 11/2 hours and then filtered. The filtrate was evaporated and the residue extracted with ethyl acetate. The solution was filtered, evaporated and the oily residue distilled to give the title compound (25.7 g, 92%) b.p. 150° C. at 0.2 mm mercury.

1. filtrationfiltered
2. customThe filtrate was evaporated
3. extractionthe residue extracted with ethyl acetate
4. filtrationThe solution was filtered
5. customevaporated
6. distillationthe oily residue distilled