Hydrochloric Acid → HCID 13287881, compound

HRID 638614Notes

Reaction equation

HRID 638614 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4](/[CH:14]=[CH:15]/[C:16]([O:18]CC)=[O:17])[CH:5]=[CH:6][C:7]=1[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1.Cl>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4](/[CH:14]=[CH:15]/[C:16]([OH:18])=[O:17])[CH:5]=[CH:6][C:7]=1[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13287878HCID 13287878, compound

Product 1

HCID 13287881HCID 13287881, compound

Procedure

A mixture of ethyl (E)-3-[3-chloro-4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate (0.1 g, 0.31 mmol) and hydrochloric acid (6M, 2.0 ml) was stirred and boiled for 2 h. The reaction mixture was then concentrated under reduced pressure, when ethanol (4.0 ml) was added and the reaction mixture was again concentrated.

Workup

  1. concentrationThe reaction mixture was then concentrated under reduced pressure, when ethanol (4.0 ml)
  2. additionwas added
  3. concentrationthe reaction mixture was again concentrated

Sources & evidence

ORD record
ord-b7b67fad2e844a39959b4989766e5833
Source dataset
uspto-grants-1985_12
Patent number
US04562199

Reaction notes

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