反应详情

A solution of 3.3. g of allyl isocyanate in 10 ml of methylene chloride is added dropwise to a mixture of 10.7 g of 2-(1,2-dichlorovinyloxy)phenylsulfonamide and 6.1 g of 1,8-diazabicyclo[5.4.0]undec-7-ene in 100 ml of methylene chloride, with stirring. When the exothermic reaction has subsided, stirring of the reaction mixture is continued at 20° to 25° C. for a further hour and the solvent is then evaporated off. The residue is dissolved in 5% sodium carbonate solution. The solution is filtered and acidified with 10% hydrochloric acid, whereupon the product precipitates as crystals. After filtration and drying, 13.2 g of N-[2-(1,2-dichlorovinyloxy)phenylsulfonyl]-N'-allylurea are obtained. Melting point: 187°-188° C.

1. customWhen the exothermic reaction
2. stirringstirring of the reaction mixture
3. waitis continued at 20° to 25° C. for a further hour
4. customthe solvent is then evaporated off
5. dissolutionThe residue is dissolved in 5% sodium carbonate solution
6. filtrationThe solution is filtered
7. customprecipitates as crystals
8. filtrationAfter filtration
9. customdrying