HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(Trifluoromethoxy)anisole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-(Trifluoromethoxy)phenol | HCID 2777299 | — |
| Product | 2-(Trifluoromethoxy)anisole | HCID 2777185 | 78% |
Reaction Steps
2-Trifluoromethoxyanisole was prepared from 2-trifluoromethoxyphenol by following Method C in 78% yield. Methyl iodide was used in this reaction as an alkylating agent and the reaction was conducted at room temperature for 17 h. The product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691843B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-76282cb9be344f6484b9ec6a540b1468 |
| Source note | uspto-grants-2010_04 |