反应详情

温度

60 °C

6-Methoxy-quinolin-4-ol (18.5 g) in acetic acid (750 mL) was treated with N-chlorosuccinimide (15.52 g) and the mixture was heated at 60° C. for 4.5 hr, cooled, and evaporated. Excess sodium bicarbonate solution was added and the solid collected and washed with water and dried in vacuo at 40° C. overnight, to give a yellow solid (21.3 g).

1. temperaturecooled
2. customevaporated
3. additionExcess sodium bicarbonate solution was added
4. customthe solid collected
5. washwashed with water
6. customdried in vacuo at 40° C. overnight