反应详情

温度

80 °C

{4-[(1,1-dimethylethyl)thio]-5-hydroxy-2-pyridinyl}methyl acetate (2.5 g, 9.8 mmol) was dissolved in concentrated HCl and the mixture was heated at 80° C. for 18 hours. The solvent was evaporated under vacuum and the residue was triturated with diethyl ether to afford the product as a solid (1.35 g, 88%); MS (+ve ion electrospray) m/z 158 (MH+).

1. customThe solvent was evaporated under vacuum
2. customthe residue was triturated with diethyl ether