Potassium Carbonate → HCID 59026168, compound

Participants

Reaction Steps

To a stirred solution of ethyl[((3S)-1-{2-[6-(methyloxy)-1,5-naphthyridin-4-yl]ethyl}-3-pyrrolidinyl)methyl]carbamate (0.80 g, 2.09 mmole) in MeOH (30 mL) and H2O (15 mL) at RT was added potassium carbonate (1.44 g, 10.5 mmole). After 18 h, the reaction contents were concentrated under reduced pressure and filtered through celite (EtOH) to give the title compound (0.59 g, 99%) as a light brown oil: LC-MS (ES) m/e 289 (M+H)+.

Provenance & Evidence