反应详情

2-chloro-6-methoxyquinazoline (1eq) and 4-bromoaniline (2 eq) in ethanol was heated at 80° C. for 16 h. The mixture was concentrated and passed through a plug of silica to yield (4-bromophenyl)(6-methoxyquinazolin-2-yl)amine.

1. concentrationThe mixture was concentrated