HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromoaniline → (4-Bromophenyl)(6-methoxyquinazolin-2-yl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromoaniline | HCID 7807 | — |
| Reactant | 2-Chloro-6-methoxyquinazoline | HCID 59254852 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Bromophenyl)(6-methoxyquinazolin-2-yl)amine | HCID 59254902 | — |
Reaction Steps
2-chloro-6-methoxyquinazoline (1eq) and 4-bromoaniline (2 eq) in ethanol was heated at 80° C. for 16 h. The mixture was concentrated and passed through a plug of silica to yield (4-bromophenyl)(6-methoxyquinazolin-2-yl)amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691866B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-7b1322decbaf43b2835931f1a6221229 |
| Source note | uspto-grants-2010_04 |