反应详情

(4-bromophenyl)(6-methoxyquinazolin-2-yl)amine in HBr was heated at 100° C. for 16 hours. The reaction mixture was concentrated and purified on preparative chromatography. Lyophillization yielded 2-[(4-bromophenyl)amino]quinazolin-6-ol.

1. concentrationThe reaction mixture was concentrated
2. custompurified on preparative chromatography