反应详情

温度

80 °C

A solution containing 2-chloro-6-methoxyquinoxaline (synthesized as described in J. Chem. Soc. Perkin Trans 2001, 978-984) (1 eq), 3-t-butylaniline (2 eq) in ethanol was heated at 80° C. overnight. The resultant mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine and dried. Purification on silica gel gave the desired product.

1. concentrationThe resultant mixture was concentrated
2. custompartitioned between ethyl acetate and water
3. washThe organic layer was washed with brine
4. customdried
5. customPurification on silica gel