2-Propanesulfonyl chloride → HCID 178461082, compound

Participants

Reaction Steps

4-isopropylsulfonylaminocyclohexanecarboxylic acid as prepared easily from methyl 4-aminocyclohexanecarboxylate with 2-propanesulfonyl chloride, and 2,3-diamino-6-(2,4-difluorophenyl)pyridine were allowed to undergo ring-closure condensation under the same conditions as described in Example 1-3), followed by separatory purification on a collective thin-layer chromatograph (chloroform:methanol=20:1) to give the title compounds.

Provenance & Evidence