Water → HCID 49771646, compound

HRID 639596Notes

Reaction equation

HRID 639596 reaction equation
[CH3:1][O:2][C:3]([C:5]1[N:10]=[C:9]([NH:11]CC2C=CC=CC=2)[C:8]2[NH:19][C:20](=[O:29])[N:21]([CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[C:7]=2[CH:6]=1)=[O:4].O>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]([C:5]1[N:10]=[C:9]([NH2:11])[C:8]2[NH:19][C:20](=[O:29])[N:21]([CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[C:7]=2[CH:6]=1)=[O:4]

Participants

4

Reactant 2

HCID 962WaterHCID 67457354HCID 67457354, compound

Product 1

HCID 49771646HCID 49771646, compoundYield 65.1%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

1-Benzyl-4-benzylamino-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester (0.02 g) was taken up in sulfuric acid (2 mL), and stirred rapidly for 15 mins. The reaction mixture was cooled to 0C, and water was added, which resulted in a precipitate which was filtered and dried in vacuo to give the title compound (10 mg) as a white solid.

Workup

  1. additionwas added
  2. customwhich resulted in a precipitate which
  3. filtrationwas filtered
  4. customdried in vacuo

Sources & evidence

ORD record
ord-0032128e8ef94bd39ad8204d45cdaa7c
Source dataset
uspto-grants-2010_04
Patent number
US07691877B2

Reaction notes

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