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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639656Generated: October 27, 2026

Thiazole → (2-Amino-3-nitro-6-thiazol-2-yl-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester

https://huagongshe.com/reaction/639656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazoleHCID 9256—
Reactant(2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl esterHCID 86614483—
Product(2-Amino-3-nitro-6-thiazol-2-yl-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl esterHCID 67457212—

Reaction Steps

The title compound was prepared following the example in preparation 70, using thiazole (42 mg) and (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester (100 mg), giving the product (79 mg) as a yellow gum.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691877B2
Source datasetuspto-grants-2010_04
ORD IDord-5c5b989f325a4d1eac8e83d3c6a0cca7
Source noteuspto-grants-2010_04