HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → (2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | (2,6-Dibromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 86614487 | — |
| Product | (2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 86614486 | — |
Reaction Steps
The title compound was prepared following the example in preparation 69 using (2,6-dibromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester (2.75 g), aqueous ammonia (11 ml), and 2-methyl-THF (11 ml). This gave the product (1.92 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691877B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-d5b40776288744e3a2c2eb7818d7bd7a |
| Source note | uspto-grants-2010_04 |