反应详情

(2-Amino-6-chloro-3-nitro-pyridin-4-yl)-benzyl-carbamic acid ethyl ester (100mg, 0.285 mmol), 4-fluoropyrazole (24.5 mg, 0.285 mmol) and potassium carbonate (118 mg 0.855 mmol) were stirred together in 5 mL of acetonitrile, under nitrogen. Heated the reaction to reflux for 3 hours and then allowed to cool to ambient temperature over night.

1. temperatureHeated
2. customthe reaction
3. temperatureto reflux for 3 hours