Trimethyl phosphite → HCID 23131723, compound
Reaction equation
Br[CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[O:7].[P:11]([O:16]C)([O:14][CH3:15])[O:12][CH3:13]>>[CH:6]([C:5]1[CH:4]=[C:3]([CH:10]=[CH:9][CH:8]=1)[CH2:2][P:11](=[O:16])([O:14][CH3:15])[O:12][CH3:13])=[O:7]Participants
3
Conditions
- Temperature
- 100 °C
Procedure
A mixture of 0.60 g of 3-(bromomethyl)benzaldehyde and 0.45 ml of trimethyl phosphite was stirred at 100° C. for 3 hours. The reaction mixture was subjected to silica gel column chromatography to obtain 0.62 g of oily dimethyl (3-formylbenzyl)phosphonate [Compound No. (x)].
Sources & evidence
- ORD record
- ord-ad0a0945207e4b2e93f1b295ed61cc0f
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07691883B2
Reaction notes
Loading…