Sodium hydride → HCID 68431011, compound

HRID 639813Notes

Reaction equation

HRID 639813 reaction equation
[I:1][C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([CH2:13][OH:14])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[H-].[Na+].[CH:17]1([N:20]2[C:24](S(C)(=O)=O)=[N:23][N:22]=[C:21]2[C:29]2[CH:34]=[CH:33][N:32]=[CH:31][CH:30]=2)[CH2:19][CH2:18]1>>[CH:17]1([N:20]2[C:24]([O:14][CH2:13][C:10]3[N:11]=[N:12][N:8]([C:4]4[CH:5]=[CH:6][CH:7]=[C:2]([I:1])[CH:3]=4)[N:9]=3)=[N:23][N:22]=[C:21]2[C:29]2[CH:30]=[CH:31][N:32]=[CH:33][CH:34]=2)[CH2:19][CH2:18]1

Participants

4

Reactant 3

HCID 24758Sodium hydrideHCID 578379334-(4-Cyclopropyl-5-methanesulfonyl-4H-[1,2,4]triazol-3-yl)-pyridineHCID 68432058HCID 68432058, compound

Product 1

HCID 68431011HCID 68431011, compound

Procedure

The title compound is prepared from [2-(3-iodo-phenyl)-2H-tetrazol-5-yl]-methanol (1 mmol), sodium hydride (1.5 mmol) and 4-(4-cyclopropyl-5-methanesulfonyl-4H-[1,2,4]triazol-3-yl)-pyridine (1.25 mmol).

Sources & evidence

ORD record
ord-62be12eabec34673923eec931754b0bf
Source dataset
uspto-grants-2010_04
Patent number
US07691892B2

Reaction notes

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